H&O Biosis

- Health.chosun.com -

An integrated natural anticancer medicine that kills hepatocellular carcinoma cells was developed. This anticancer medicine by H&O Biosis showed the effects of apoptosis and anti-proliferative activities on liver cancer cells in both in-vivo and animal testing. 

This new antitumor medicine reduced the growth of the hepatocellular carcinoma cell line (Huh-7) by 50% in animal experiments. According to the blood test, the toxicity of the medicine was low, thus adverse effects are expected to be low level.

Up until now treatments for hepatocellular carcinoma have mainly relied on physical treatments such as transarterial chemoembolization, radiofrequency therapy, and liver transplantation.  In addition to having insignificant effectiveness, most liver cancer drugs have severe side effects such as skin reactions, vomiting, and diarrhea caused by its toxicity.  This makes their administration limited. On the other hand, the integrated natural anticancer medicine is expected to alleviate the pain of liver cancer patients by minimizing toxicity and adverse effects.

Dr. Park Jong-Min of H&O Biosis said, “We are preparing for approval for phase 1 clinical trial in 2024, and we will open the way for the least painful treatment possible for hepatocellular carcinoma patients by proving its efficacy as a first-line anticancer drug (or integrated natural anticancer medicine)."

Meanwhile, the result of this experiment is recently published in the international journal ‘Cancers’.

Health.chosun.com / Feburary 17, 2023